812 Multi-view light sheet florescence microscopy (LSFM) for imaging cellular self-assembly in spheroids of human hair follicle dermal papilla cells and keratinocytes
نویسندگان
چکیده
منابع مشابه
hair follicle generation by injecting adult human follicular epithelial and dermal papilla cells in nude mice
objective: objective: dermal papilla and hair epithelial stem cells regulate hair formation and growth cycle. damage to or losing of these cells can cause hair loss. although several studies have claimed to reconstitute hairs using rodent cells in animal model, a stable human hair follicle reconstitution protocol needs more studies. here in this study we evaluated hair induction through injecti...
متن کاملRegulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle.
Platelet-derived growth factor (PDGF) is a potent mitogenic factor for many cell types and has been shown to be important in follicular development and vasculogenesis. In this study, we examined the expression pattern of both PDGF factors and their corresponding receptors in mesenchyme-derived dermal papilla cells (DPCs) and epithelial follicular keratinocytes (FKs). Both types of PDGF receptor...
متن کاملDissociated human dermal papilla cells induce hair follicle neogenesis in grafted dermal-epidermal composites
Cells. Human dermal papilla cells isolated from temporal scalp dermis (Promocell, Heidelberg, Germany) from five female donors (HDP41, HDP43, HDP44, HDP47, and HDP52) and one male donor (HDP60), named according to donor age in years, were propagated in vitro according to manufacturer’s recommendations. Keratinocytes were isolated from neonatal foreskins and were cultured in serum-free medium (K...
متن کاملHair follicle dermal papilla cells at a glance.
Ryan R. Driskell1, Carlos Clavel2, Michael Rendl2,* and Fiona M. Watt1,3,* 1Laboratory for Epidermal Stem Cell Biology, Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge CB2 1QR, UK 2Black Family Stem Cell Institute and Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029, USA 3CRUK Cambridge Research Institute, ...
متن کاملA review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration
Alopecia is an exceedingly prevalent problem effecting men and women of all ages. The standard of care for alopecia involves either transplanting existing hair follicles to bald areas or attempting to stimulate existing follicles with topical and/or oral medication. Yet, these treatment options are fraught with problems of cost, side effects, and, most importantly, inadequate long-term hair cov...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2020
ISSN: 0022-202X
DOI: 10.1016/j.jid.2020.03.827